| Product Name: |
DSIP |
| CAS: |
62568-57-4 |
| MF: |
C35H48N10O15 |
| MW: |
848.82 |
| EINECS: |
211-519-9 |
| Boiling point |
1522.7±65.0 °C(Predicted) |
| density |
1.458±0.06 g/cm3(Predicted) |
| storage temp. |
−20°C |
| pka |
3.18±0.10(Predicted) |
| form |
Powder |
| color |
White to off-white |
| Water Solubility |
Soluble in water at 0.5mg/ml |
DSIP is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
DSIP was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.
DSIP-like material has been found in human breast milk.
DSIP Roles in endocrine regulation
· Decreases basal corticotropin level and blocks its release.
· Stimulates release of hormone.
· Stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatin secretion.
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